Logitech Harmony One Universal Remote
I am totally in love with it. Manages everything that we have in our house, and we do have a lot! (we are a bit geeky at home so there is tv, audio, home made tivo through a computer, DVD, etc etc). Have it for a couple of months and so far flawless. Easy to setup, easy to use, the backlit makes it everything easier. Even easy to troubleshoot if you have a problem!