For a weekend getaway, nothing beats a Tumi carry-on. Reliable and sophisticated, this will happily hold your prized possessions and fit comfortably in an overhead compartment. Another plus is the internal garment bag and other accessories pockets to organize your goods, and it even expands if you do too much shopping while away.

T3 Transporter 22" Expandable Wheeled Packing Case with Suiter is one of the best carry-ons around. I got one for my husband and he loves it. It's good for 4-6 day trips and allows you to include a suit and has special accessory pockets. This is great for the Dad (or husband) who travel a lot.