At Tablet Hotels (www.TabletHotels.com) you can research, see superb photos, and book the lowest rates for luxury boutique hotels. They have the hotels you'd expect (Mercer, Soho Hotel, Raleigh) and some you'd never find elsewhere (The Commune, Therme Bath Vals). (via Beth Callas)

Take my word for it this is THE best site to book an hotel from. It is so easy to use has great hotels and great deals. The customers rate the hotels and they are removed if their rating goes down too low. I've been using it for years now.